RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
Bmper
RNA ID
RNA Type
mRNA
Alteration Pattern
dna methylation
Species
mus musculus
Detection Methods
Dual-luciferase reporter assay; ELISA etc.
Target
NA
Pathway
TGF-B/BMP signaling pathway
PubMed ID
Title
Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivo
Year
2015
Function
"BMPER is highly expressed in human IPF lung fibroblasts compared to normal lung fibroblasts. Demethylation agent 5'-azacytidine decreased BMPER expression in fibroblasts, and attenuated the invasion and migration of IPF lung fibroblasts."